SARMS is believed to have the capacity to employ the benefits of anabolic supplements while reducing the side effects of steroids.
Non-toxic (won’t cause liver damage)
Avoids bone loss (direct action of testosterone in bone thru the AR-mediated conduit is critical for its anabolic effects in bone)
Decreases the threat of prostate problems in men without muscle mass loss
Won’t impede your HPTA
Similar effects with testosterone
No estrogen and Dihydrotestosterone (a hydrogen hormone) conversion
For muscle builders, taking SARMS will give:
Muscle loss prevention (during the cutting period)
Lean muscle development
Improved strength
Faster injury recovery
Joint healing abilities
PCT use following anabolics
Increased muscle strength
In the Asian Journal of Andrology, subjects increased muscle strength 20x more than those in the placebo group. Subjects continued to gain strength and size in muscle tissue for up to 5 months but with significant decreases in effectiveness after the 3rd month.
Increased muscle size
Deductive evidence has proven a significant increase in muscle tissue hypertrophy (growth of muscle tissue). Inductive evidence suggests subjects will gain between 3 to 15 lbs of muscle tissue over the a 12 week period. The amount of muscle hypertrophy is dependent on diet, training, and the characteristics of the SARM. Mild SARMs such as MK2866 will range much lower in hypertrophy than more potent SARMs such as RAD140 or LGD4033.
Tissue selectivity
According to the Oxford Academic journal of Endocrinology, nonsteroidal SARMs have been designed to attach itself to an area of the DNA responsible for skeletal muscle protein synthesis. Unlike other anabolic agents, nonsteroidal SARMs do not affect any other tissues in the body.
Inhibits cancer cell division
In an unrelated study to muscle growth performed by the Public Library of Science’s (PLOS) Peer-Reviewed Open Access Journal, nonsteroidal SARMs have been studied for its effects on breast cancer. Androgen receptors are known to play a pivotal role in the treatment of breast cancer and due to the inability for nonsteroidal SARMs to convert to estrogen, there is a very narrow probability for negative repercussions. The results have not only confirmed that tumor cells decrease in weight by 90%, but it may even inhibit the potential for breast cancer development.
Regulation of libido
Recent studies have indicated healthy increases in sexual desire in both men and women with the use of nonsteroidal SARMs. The males with hypogonadism, testosterone therapy is a common practice. In testosterone therapy there are many side effects that result is severe consequences for the user, such as thickening of the blood (commonly causing strokes and heart attacks), enlargement or development of cancer on the prostate, and gynecomastia (characterized as the development of female breast on men) due to an overproduction of estrogen. A 2014 article published by the Asian Journal of Andrology stated “SARM’s beneficial pharmacology and desirable pharmacokinetics offer considerable promise in the treatment of late onset hypogonadism. The convenience of once daily oral therapy combined with defined safety margins surrounding a proven efficacious dosage form may one day challenge testosterone replacement therapy as the gold standard in treating late onset hypogonadism”.
Safety and tolerability
In the Oxford Journal of Gerontology Series A: Biological Sciences and Medical Sciences, the popular nonsteroidal SARM LGD 4033 (Ligandrol) has been recently studied for it’s effectiveness and safety in healthy young men. Results were favorable indicated by hormone and lipid levels returning to normal without the use of a post cycle therapy. No dangers were detected throughout the study.
Although there was noticeable suppression in testosterone and HDL cholesterol, it was not significant enough to cause adverse reactions. Because LGD 4033 is considered one of the strongest and most potent nonsteroidal SARMs available, it is not likely that less potent SARMs will produce any harmful effects.
Side Effects of SARMS
What’s great about SARMS is that the side effects are minimal, so you don’t have to worry about any negative effects. If you overdo it, however, some people may experience shut down or even gynecomastia if currently predisposed to it.
Be responsible, and in 99.9% of cases, users will not have any side effects from the use of SARMs. Current research has so far agreed with that conclusion.
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